US Drugstore and Pharmacy Retailing: Market Forecast and Competitive Landscape—The Pharmacy Shakeout

Uncover how shifting market dynamics, economic headwinds and consumer trends are reshaping US drugstore and pharmacy retail.

Read this report to discover answers to these and other questions:

• What is the 2025 growth outlook for the US drugstore and pharmacy market—and which segments are driving it?
• Which retailers are gaining and losing market share in the evolving drugstore and pharmacy landscape?
• Which are the top-performing retailers and brands and how are non-specialists and marketplace leader Amazon changing the game?
• What macro and demographic forces—from inflation to aging consumers—are influencing demand, pricing and relevance in the sector?

Data in this report include: total market size and segment forecasts through 2029; e-commerce penetration trends; store counts and traffic data by retailer; operating margins by retailer; and results from Coresight’s July 2025 US consumer drugstore and pharmacy survey.

Introduction

Coresight Research Analysis: The Pharmacy Shakeout—Consolidation, Competition and the Digital Pivot

The Sector

• Market Scale and Opportunity
• Segment Breakdown
• Market Factors

The Companies

• Competitive Landscape: Retailers
• Store Metrics
• Retailers’ Store Traffic

The Consumer

• Where Consumers Are Shopping and What They Are Buying

What We Think

• Implications from This Report
• Implications for Brands/Retailers
• Implications for Real Estate Firms
• Implications for Technology Vendors

Notes and Methodology
Appendix

23-page PDF report

Albertsons Companies, Amazon, CVS Health, Costco, Dollar General, Dollar Tree, Family Dollar, Health Mart, Kroger, McKesson, Publix, Rite Aid, Walgreens and Walmart.

• US Drugstores and Pharmacies’ Total Sales and YoY Change
• 2024 US Drugstores and Pharmacies: Estimated Sector Sales by Category and Major Drugstore Chains: Proportion of Retail Sales Accounted for by Pharmacy Sales
• US Drugstores and Pharmacies: Total OTC/Nonprescription/Personal Care Products In-Store and Online Channel Share and Major Drugstore Chains: Proportion of Retail Sales Accounted for by Pharmacy Sales
• Health Category: E-Commerce, In-Store and Total Sales Growth
• Health Category: Sales by Channel and Each Channel’s Share of Total Sales
• US and Drugstore and Pharmacy Retailers’ Online Sales and YoY Change
• US Drugstore and Pharmacy Retailers’ E-Commerce Penetration Rate
• List of Certain Medications Pharmacists Can Prescribe
• YoY Inflation in Prescription (Rx) and Nonprescription Drugs in the US
• Pharmacies and Drugstores PPI Vs. Prescription Drugs CPI (YoY % Change)
• YoY Inflation (% Change in CPI) in Personal Care, Food-at-Home and Beauty Products in the US
• Leading US Drugstore Chains and Pharmacies: US Revenues (USD Bil.)
• US Drugstores: Operating Margins (%)
• US Drugstore and Pharmacy Landscape: Key Comparable Metrics of Selected Retailers
• Major Drugstore Chains and Pharmacies: US Store Numbers
• Major Drugstore Chains: Total Gross Square Feet (Ranked by FY24 Revenue; Mil. of Sq. Ft.)
• Major Drugstore Chains: Sales Per Store (Ranked by FY24 Revenue; USD Mil.)
• Major Drugstore Chains: Sales Per Square Foot (Ranked by FY24 Revenue; USD)
• US Major Drugstore Retailers’ Store Traffic: YoY % Change
• Respondents Who Purchased from a Drugstore or Pharmacy in the Three Months to April 2025: Retailers Purchased From (% of Respondents)
• Respondents Who Purchased from a Drugstore or Pharmacy in the Last Three Months: Categories Purchased (% of Respondents)
• Respondents Who Purchased from a Drugstore or Pharmacy in the Last Three Months: Reasons for Choosing to Shop at the Drugstore/Pharmacy They Use Most Often (% of Respondents)
• Respondents Who Purchased from a Drugstore or Pharmacy in the Last Three Months: Services They Use at Drugstore/Pharmacy (% of Respondents)
• Top 40 US Pharmacy Retailers in the US, by Number of Stores
• Top 50 Cannabis Retailers in the US, by Number of Stores